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With more and more people using Twitter for personal and professional reasons, the demand for a Twitter client to match these multifaceted needs is on the rise. Popular choices include TweetDeck, Seesmic (with no limits on the number of accounts you want to add), DestroyTwitter etc which are free and can be used from your desktop, phone, or on the web. As browser add-ons, try Echofon (formerly Twitterfox), a Firefox extension where you can toggle through multiple accounts in column view, Chrome Bird, for Google Chrome, or Adjix2TwitterLink, a bookmarklet by adjix that simply allows you to tweet links while browsing the web, but since you can specify which account to tweet from each time, this can be extremely handy at times.